Wednesday, February 7, 2018

Varicella Variations

One of the striking changes that has occurred during my career is the almost total disappearance of chicken pox in the United States. When I started out, chicken pox was commonplace, almost like seeing someone with strep throat. And it was not unusual for us to have children in the hospital with complications of chicken pox. But now that we routinely vaccinate children for it, I had not seen a case for years until I was in Zambia in July.

I was in a makeshift clinic in a mud brick building and a child was brought in by his mother for a rash which was the classic “dew drop on a rose petal” of chicken pox. He was not particularly ill and everything else was normal and I discussed with his mother through the interpreter what to expect as the illness ran its course.
It was not until they were gone that I realized the Zambians I was working with were surprised (appalled?) at my nonchalance. In their context, without routine vaccination, chicken pox remains a formidable foe. Because many folks lack easy access to clean water, they are more likely to see skin lesions which have become secondarily infected with bacteria. And due to limited transportation and access to medical care, the secondary infections can become severe before they come to medical attention.

So they typically treat aggressively with a combination of an antiviral called acyclovir and antibiotics such as dicloxacillin to prevent secondary skin infections. While this type of treatment would seem excessive in our context, it was a good reminder that chicken pox is not always a benign disease. Prior to the introduction of the vaccine, about 100 children died of chicken pox complications in the United States each year.

When an illness becomes a sort of historical footnote, it is easy to forget the misery it caused in the past, even if you saw some of that misery first-hand 25 years ago. And remaining pockets of diphtheria, polio and measles remind us that without continued vigilance, these diseases could jump out of history right back into our present.